Memory of a Killer just delivered its most gripping episode yet. Season 1, Episode 6 — titled “Uncle Jacob” — is where the show truly finds its footing, cranking up psychological tension by combining Patrick Dempsey’s best work of the season with a ticking-clock diagnosis, a high-tech public assassination, and a betrayal that reframes everything.

Memory of a Killer Episode 6 Overview

Detail	Info
Show	Memory of a Killer (Season 1)
Episode	Episode 6 — “Uncle Jacob”
Network	FOX (streaming on Hulu)
Lead Actor	Patrick Dempsey as Angelo Doyle
Based On	Belgian novel De Zaak Alzheimer
Key Revelation	Angelo diagnosed with early-onset Alzheimer’s
Mission	Assassinate Russian mob accountant Gene Handsen on live TV

What Is Angelo’s Task in Episode 6?

Angelo is given a high-stakes assignment by Dutch — to assassinate Gene Handsen, a Russian mob accountant, during a live television broadcast. The plan involves using a transmitter to disrupt Handsen’s Implantable Cardioverter-Defibrillator, ensuring the hit occurs in public.

Angelo and Joe take out Handsen, a money launderer who flipped on the Russians, using a rigged microphone to induce a heart attack during a live TV broadcast. It’s insane, inventive and deeply dark.

The ingenuity of the kill showcases exactly why this show is worth watching — but it’s what happens off the job that hits hardest.

The Alzheimer’s Diagnosis — Angelo’s World Tilts

Memory of a Killer takes the bold step in Episode 6 of confirming what we all suspected — that Angelo is suffering from early-onset Alzheimer’s, like his brother before him, and there’s no cure. Some drugs are offered that’ll slow the decline, but nothing is going to stop it. Angelo’s fate is sealed. Ready Steady Cut

The doctor tells Angelo that the MRI shows atrophy in the main memory areas. Along with his family history, this likely means early-onset Alzheimer’s disease. Angelo asks how long he has. The doctor says everyone progresses differently, but there is nothing he can do to stop the progression of the disease. The Review Geek

Early-onset Alzheimer’s disease typically affects people under 65, and for a hitman whose entire survival depends on precision memory, the diagnosis isn’t just personal — it’s operationally catastrophic. Angelo leaving a security guard in a stairwell after hallucinating his brother was a massive rookie mistake. The memory issues aren’t just a plot point anymore — they’re becoming a liability. Fangirlish

The Cliffhanger Ending: Nicky’s Betrayal

Angelo tries to set a trap for the mysterious Ferryman, suspecting Nicky. But the plan backfires completely. Instead of showing up to the trap, Nicky visits his doctor, threatening him until he hands over Angelo’s medical records — including his Alzheimer’s diagnosis. Ready Steady Cut

Does this mean we cannot trust Nicky? Does this mean she is actually working for the Ferryman? The show does a great job of always making us second-guess who we can and cannot trust. Paste Magazine

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FAQs

Q: What is Angelo’s task in Memory of a Killer Season 1 Episode 6?

Angelo is assigned to assassinate Russian mob accountant Gene Handsen during a live TV broadcast, using a transmitter to trigger a fatal malfunction in Handsen’s pacemaker — his most technically daring hit yet.

Q: Does Angelo get officially diagnosed with Alzheimer’s in Episode 6?

Yes — Episode 6 confirms Angelo has early-onset Alzheimer’s disease, a condition with no cure, marking a turning point where his memory lapses shift from subtle hints to a dangerous, life-threatening liability.