How to Cure Vampirism in Oblivion Remastered: 3 Proven Methods for 2025

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The Elder Scrolls IV: Oblivion Remastered has brought a beloved classic back to life with enhanced graphics and gameplay, but some challenges remain as formidable as ever—particularly the curse of vampirism. While becoming a vampire in Cyrodiil grants impressive powers like enhanced strength, speed, and unique abilities, many players quickly discover the severe drawbacks: vulnerability to fire, inability to travel during daylight, and being locked out of numerous quests.

What initially seems like an exciting transformation can rapidly become a frustrating hindrance to your adventure. Whether you contracted Porphyric Hemophilia accidentally while exploring a forgotten cave or deliberately embraced the dark gift only to regret your decision, finding a cure becomes an urgent priority for continued enjoyment of the game.

Fortunately, Oblivion Remastered offers multiple paths to rid yourself of vampirism, each with its own requirements, timeline constraints, and consequences. From simple solutions that work in the early stages of infection to elaborate quests involving powerful witches and rare ingredients, the game provides options regardless of how long you’ve been afflicted.

This comprehensive guide explores all three methods to cure vampirism in Oblivion Remastered, detailing the specific steps, required items, and potential complications for each approach. Whether you’re a novice adventurer who just contracted the disease or a long-term vampire seeking redemption, these solutions will help you return to normal life in the vibrant world of Cyrodiil.

Method 1: Early Intervention (Within 72 Hours)

The simplest way to cure vampirism in Oblivion Remastered is to act quickly before the disease fully takes hold. After being infected with Porphyric Hemophilia, you have a 72-hour window to treat it as a standard disease before it progresses to full vampirism. During this critical period, several common remedies can purge the infection from your system.

The most accessible option is to consume a Cure Disease potion, which can be purchased from alchemists throughout Cyrodiil or found in dungeon chests. Alternatively, if your character has access to restoration magic, casting a Cure Disease spell on yourself will achieve the same result. Nature’s remedies also offer solutions—consuming either a Mandrake Root or a Shepherd’s Pie will cure the disease. For the spiritually inclined, simply praying at any Wayshrine, Temple, or Shrine will bestow blessings that include disease curing.

This method is particularly valuable for players who accidentally contract the disease and notice the symptoms early. The key advantage is simplicity—no complex quests or rare ingredients required. However, the strict 72-hour time limit means you must remain vigilant about your character’s health status. If you miss this window, you’ll need to pursue one of the more involved cures described below.

Method 2: The Deepscorn Hollow Solution

If you’ve passed the 72-hour threshold and fully transformed into a vampire, the Deepscorn Hollow method offers a relatively straightforward solution, though with a permanent consequence. This approach requires accessing a special underwater location and using a unique purification ritual.

Begin by traveling to Deepscorn Hollow, an underwater cave located south of Leyawiin Castle. Once inside, navigate to the Deepscorn Cloister area and take the left path to locate the Font of Renewal monolith. When you first interact with it, you’ll receive a message indicating you need Purgeblood Salts to proceed. These salts can be found in the same room—look for a rocky formation called the Purgeblood Crystal Formation in a corner of the chamber. Interact with it to collect the salts, then return to the Font of Renewal to complete the ritual and cure your vampirism.

While this method is more accessible than the lengthy quest option, it comes with a significant caveat: using the Font of Renewal permanently immunizes you against Porphyric Hemophilia. This means you can never become a vampire again in your current playthrough. For players who are certain they want to permanently avoid vampirism, this is ideal. However, if you might want to experience vampire abilities in the future, consider the third method instead.

Method 3: The Vampire Cure Quest

The most involved but narratively rich option for curing vampirism is the aptly named “Vampire Cure” quest. This method works regardless of how long you’ve been a vampire and doesn’t prevent future infections, making it ideal for players who want to keep their options open.

To begin this quest, speak with any healer NPC or Vicente Valtieri (if you’re a Dark Brotherhood member) about your condition. They’ll direct you to Raminus Polus at the Arcane University, who will then send you to meet Count Janus Hassildor at Castle Skingrad. At the castle, speak with the steward Hai-Liurz to arrange an audience with the Count. Janus will reveal that a Glenmoril Witch near the Corbolo River might help, and a marker for Drakelowe will appear on your map.

At Drakelowe, you’ll meet Melisande, who agrees to help but requires several rare components. First, she needs five empty Grand Soul Gems, which can be found in three nearby locations: Crayfish Cave, Nornal, and Squandered Mine. You’ll need to find two additional gems through general exploration, as they’re commonly found in treasure chests throughout Cyrodiil.

After delivering the soul gems, Melisande will request specific ingredients for the cure potion:

  • Two Bloodgrass plants (found inside Oblivion Gates)
  • Six Garlic cloves (commonly found in homes)
  • Five Nightshade plants (found in West Weald or purchasable from The Main Ingredient in Imperial City)
  • Blood of an Argonian (obtained using Melisande’s enchanted dagger on any Argonian without killing them)
  • Ashes of a powerful vampire (acquired by defeating Hindaril at Redwater Slough)

Once you’ve gathered all ingredients, return them to Melisande, who will ask you to return after 24 hours. When you come back, she’ll provide two Cure for Vampirism potions. Drink one to cure yourself, and deliver the second to Count Janus for his wife to complete the quest and receive a gold reward.

This method offers the most comprehensive solution without permanent consequences, allowing you to experience all aspects of Oblivion Remastered’s gameplay, including the possibility of becoming a vampire again in the future if desired.

Comparison of Vampirism Cure Methods in Oblivion Remastered

MethodTime RequirementItems NeededDifficultyCan Become Vampire Again?
Early InterventionWithin 72 hours of infectionCure Disease potion, Mandrake Root, or Shrine blessingEasyYes
Deepscorn HollowAny time after full transformationPurgeblood SaltsMediumNo (permanent immunity)
Vampire Cure QuestAny time after full transformation5 Grand Soul Gems, 2 Bloodgrass, 6 Garlic, 5 Nightshade, Argonian Blood, Ashes of HindarilHardYes

Pros and Cons of Being a Vampire in Oblivion Remastered

ProsCons
Enhanced strength and speedVulnerability to fire damage
Night Eye abilityCannot travel during daylight without damage
Unique vampire-specific powersNPCs may refuse to interact with you
Immunity to diseaseLocked out of certain quests
Increased stealth capabilitiesNeed to feed regularly to manage symptoms

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FAQs

Q1: Can I become a vampire again after curing myself in Oblivion Remastered?


A1: It depends on which cure method you use. If you cure vampirism using the Deepscorn Hollow method (Font of Renewal), you’ll gain permanent immunity to Porphyric Hemophilia and can never become a vampire again in that playthrough. However, if you use either the early intervention method or complete the Vampire Cure quest, you can become infected and transform into a vampire again later.

Q2: What are the early signs that I’ve contracted Porphyric Hemophilia in Oblivion Remastered?


A2: Watch for a message stating “You feel a strange thirst coming on…” after sleeping. You may also notice the disease listed in your active effects menu. If you see these signs, you have 72 hours of game time to cure the disease before it progresses to full vampirism. During this window, standard disease cures like potions or shrine blessings will work.

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