Stuck searching for Great Mullein in ARC Raiders? This uncommon medicinal plant is essential for healing crafts, Lance’s Doctor’s Orders quest, and generating currency through Celeste. While it spawns across all four maps, knowing the prime locations saves hours of wandering. Here’s your definitive guide to efficiently farming this valuable resource.
Table of Contents
ARC Raiders: Best Great Mullein Farming Locations
| Location | Map | Spawn Rate | Safety Level | Plants Per Visit |
|---|---|---|---|---|
| Hydroponic Dome Complex | Dam Battlegrounds | Very High | Medium | 6-10 plants |
| Testing Annex (Pool Room) | Dam Battlegrounds | High | Medium | 3-5 plants |
| Red Lakes Swamp | Dam Battlegrounds | High | Low | 4-8 plants |
| Galleria Planters | Buried City | Very High | Low (PVP) | 12-15 plants |
| Blue Gate Forests | Blue Gate | Medium | High | 1-3 plants |

What is Great Mullein?
Great Mullein is an uncommon item used for medical supplies and can be recycled into Assorted Seeds. Visually, it’s a knee-high plant with large green leaves and distinctive pink-red flowers on top. Unlike mechanical loot found in containers, you harvest Great Mullein directly from the environment near water sources and hydroponic areas.
For more survival tips, check our ARC Raiders beginner’s guide and crafting essentials.
Prime Location #1: Dam Battlegrounds
Hydroponic Dome Complex (Best Overall): This geodesic greenhouse structure is your Great Mullein goldmine. Head to the Hydroponic Dome Complex where large rectangular ponds contain plantlife growing at the edges. You’ll consistently find 6-10 plants per visit.
Warning: The area is almost always patrolled by wasps, with roller-ball enemies or spider-like enemies lurking inside the ponds. Clear enemies first or use stealth to harvest safely.
Testing Annex (Most Reliable): The Testing Annex on Dam Battlegrounds has a bottom floor pool of water that almost always has multiple spawns of this plant available. This location doubles as an excellent spot for finding Antiseptics, Syringes, and Durable Cloth for Lance’s quest.
Red Lakes & Old Battleground Swamp: Both areas regularly spawn multiple plants per visit, making them efficient loops if you need to stockpile. The swamp region offers fewer enemy encounters than the Hydroponic Dome.
Prime Location #2: Buried City
Galleria Planters (Highest Yield): The first floor of the Galleria has several planters with three Great Mulleins per planter, and grabbing them all can net you around 15 per trip—the highest single-location yield in the game.
The Catch: Buried City is a prime PVP map with heavy ARC enemy presence. The Buried City’s Hospital gives you more lootable containers but it’s a prime map for PVP and has more enemies to deal with. Only visit if you’re geared for combat or traveling with a squad.
Improve your combat readiness through our ARC Raiders PVP tactics and enemy guide.

Alternative Sources
Celeste the Trader: She has 10 Great Mullein in stock at any given time, and will part ways with one for just five Assorted Seeds. If you’re flush with seeds but short on time, this is your fastest option.
Nature-Tagged Locations: Prioritize any POI or sub-biome tagged as Nature—most plant types, including Great Mullein, can appear there. Check your map for green nature icons.
Blue Gate Forests: Great Mullein spawns in forested regions around the Ruined Homestead, Checkpoint, Highway Collapse, Forest Airshaft, and Trapper’s Glade. While spawns are sparse (1-3 plants), this map offers the safest farming environment.
Crafting Uses & Value
Herbal Bandages: Basic healing item requiring 1 Great Mullein Antiseptic: Requires 10 Chemicals + 2 Great Mullein at Refiner Level 2 Assorted Seeds: Recycle Great Mullein for Celeste’s currency Doctor’s Orders Quest: 1 Great Mullein required for Lance’s first quest
Practical loop: farm Mullein in Dam (Red Lakes / Hydroponic Dome swamp), grab Chemicals along the way, and craft Antiseptic at Refiner 2 once you’re back, keeping a few plants aside for bandages or turn-ins.
Learn more about resource management in our ARC Raiders economy guide and quest walkthrough.
Optimal Farming Route
- Drop into Dam Battlegrounds
- Hit Hydroponic Dome Complex (6-10 plants)
- Clear Testing Annex pool room (3-5 plants)
- Sweep Red Lakes swamp area (4-8 plants)
- Extract with 13-23 Great Mullein per run
This route balances safety, efficiency, and yield. Dam Battlegrounds will be the safest, as only a few of the more dangerous ARC enemies such as Rocketeers spawn, and you have plenty of cover away from them.
Pro Tips
- Always check water-heavy areas—Great Mullein spawns near moisture
- Use your Safe Pocket for rare medical supplies, not common plants
- Farm during off-peak hours to avoid already-harvested locations
- Consider recycling excess Mullein into seeds for Celeste trades
For official updates and patch notes, visit the ARC Raiders Steam page.
Frequently Asked Questions
Can Great Mullein be crafted or only harvested in ARC Raiders?
Great Mullein cannot be crafted—it must be harvested from natural spawns on topside maps or purchased from Celeste for 5 Assorted Seeds each (10 stock limit). However, you can recycle Great Mullein back into Assorted Seeds, creating a currency conversion loop. The plant spawns naturally in Nature-tagged locations, particularly near water sources and hydroponic environments. Focus your farming on Dam Battlegrounds’ Hydroponic Dome Complex and Testing Annex for the most reliable harvests.
What’s the fastest way to complete Doctor’s Orders quest for Lance?
The single-run strategy focuses on Buried City: grab 12-15 Great Mullein from Galleria planters, then loot the Hospital for Antiseptics, Syringes, and Durable Cloth. However, if you want safer farming with lower PVP risk, use Dam Battlegrounds—collect Great Mullein from Hydroponic Dome or Testing Annex, then thoroughly search Testing Annex’s upper floors for medical supplies. Both routes work, but Dam offers better safety while Buried City offers speed. Always use your Safe Pocket for rare Syringes and Antiseptics to guarantee extraction.







